Transmembrane proteins are a kind of integral membrane protein. They go across the whole plasma membrane and very often function to facillitate the transportation of various substances through the plasma membrane.
(IUCr) Approaches to ab initio molecular replacement of α-helical transmembrane proteins
Genetic Variant Increases Testicular Cancer Risk Also Evolved To Protect Light Skin - Using a genomic analysis, a team of international researchers has identified a specific mutation responsible for a dramatic increase in the risk for testicular cancer.
Cell membranes isolate the cellular environment from its surroundings, providing protection from outside influences. These membranes are covered by transmembrane proteins, which act as "gateways" for communication between the inside and outside of the cell. CXCR4 is a transmembrane protein that plays a significant role in the immune system, and is important for the recruitment of white blood cells. Unfortunately, the HIV virus utilizes CXCR4 as an entry point into host cells, propagating…
2016- Of note-The addition of 0.2% glutaraldehyde to 4% paraformaldehyde served to minimize antibody-induced clustering artifacts affording the least lateral membrane diffusion of transmembrane proteins when compared to various commonly used fixatives, including paraformaldehyde alone and methanol (Scarselli et al., 2012).