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There are also studies which include reports of psilocybin mushrooms sending both obsessive-compulsive disorders (OCD) and OCD-related clinical depression into complete remission. Recent studies done at Imperial College London and Johns Hopkins School of Medicine conclude, when used properly, psilocybin acts as an antidepressant as suggested by fMRI brain scans.
"Researchers at the Psychiatric University Hospital of Zurich have now shown that psilocybin, the bioactive component in the Mexican magic mushroom, influences the amygdala, thereby weakening the processing of negative stimuli.